Histopathology by Advanced Molecular Pathology Lab @ IMCB

Key Service

Quality Histopathology Service to Enable Your Research Advanced Molecular Pathology Laboratory (AMPL) from Institute of Molecular & Cell Biology (IMCB) is a GLP-certified histopathology laboratory that provides an integrated array of services to biomedical and pharmaceutical industries. It brings together expertise across multiple disciplines to provide a one-stop histology services. New technologies at AMPL enable research groups to deliver innovative and cutting-edge contribution to basic as well as translational research, therapeutic target validation and drug safety evaluation. AMPL handles rodent and non-rodent tissues, we offer well-established SOPs and advanced equipment to provide histo services. • Rodent necropsy • Laser capture microdissection (LCM)* • Routine and specialised histology processing* • Tissue microarrays (TMA)* • Cryo tissue processing and cryotomy* • Veterinary pathology evaluation* • Special Staining* • Veterinary diagnostic services • Immunohistochemistry and immunofluorescence* • Quality assurance at each step of service • Antibody evaluation and optimisation • GLP in vitro toxicity testing facility (in progress) • Quality scanning and digital imaging* • Image analysis*

Key Equipment

• Milestone MacroPATH D Macro Digital Imaging • Olympus stereo microscope • SAKURA ® Tissue-Tek® VIP® and Tissue-Tek ® Tec™ • Leica RM Microtome • Leica Autostainer • Leica IPC, IPS-Slide and cassette printer • IHC-Leica Bond-Max™ and Leica Bond-III™ • Leica SCN400 scanner • Leica whole slide image analysis • Metasystem fluorescence scanner • Beecher Manual Tissue Arrayer MTA-1 • Carl Zeiss PALM Microbeam • Nikon90i automated microscope bright field/fluorescent

Accreditations

• AMPL is a GLP-certified lab certified by Singapore Accreditation Council (SAC) • Veterinary pathologists are American board certified either in pathology or toxicology